Yo-Yo dieting may significantly Increase Kidney Disease Risk in People with Type 1 Diabetes

Yo-Yo dieting may significantly Increase Kidney Disease Risk in People with Type 1 Diabetes


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Body-and-Vest Cycling (Also Known as Yo-Yo Dieting) Raditional Risk Factors, According to a Study Published in the Journal of Clinical Endocrinology & Metabology.

Yo-yo dieting is defined as reepeated losing and gaining weight multiple times over the year. Its prevalence is reported to be as high as 35% in men and 55% in women.

This pattern of dieting has been shown to increase risks of Cardiovascular Events in Bot the General Population and in People with Type 2 Diabetes, and more recently in type 1 diabetes.

This is the first study to show a link between yo-yo dieting and kidney events in people with type 1 diabetes, according to the authorities. Type 1 diabetes was long consides a disease of lean individuals. But as with the general population, the prevalence of obesity is a risk amon with type 1 diabetes as well, the authors note.

“We showed that high body-white variables is associated with Increased Risk of Different Outcomes of Diabeetic Kidney Disease (DKD) Progressions in People’s 1 Adightal Dkd Risk Factors, “said lead author marion camune, md, of the Center Hospitalier Universitaire de Bordeaux, France. “To our knowledge, this is the first study showing this association.”

Researchers from France Examined Six Years of Body-White Indices for the 1,432 Participants in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Deebery Y.

The primary index for identifying yo-yo dieting patterns in the study was knowledge as “variable independent of the meaning” (VIM) (VIM) (VIM) (VIM) (VIM) (VIM) (VIM) (VIM), which measures fluctuations worth and beLow a perceon ‘.

Using the weight fluctuation data, Researchers Examined Six Criteria for Kidney Function Decline and Progression towards Chronic Kidney Disease. Their primary Criteria was the “estimated glomerular filtration rate” (egfr), which measures how wall the kidneys filter toxins from the blood.

Participants with great weight fluctuations experience a 40% decline in egfr from baseline values, according to the study. Thos with great weight fluctuations also was more likely to exhibit moderately and severely increase albuminuria, a condition in which the protein albumin is abnormally present in the urine. Larger Amounts Occur in the Urine of Patients with Kidney Disease.

Similar Findings of Kidney Disease Were Confirmed by the other examined indices.

Potential Risk Factors of Body-Whight Cycling

The pathophysiological mechanisms Linking Body-Andight Cycling to Renal Risk Are Still Not Fully Understood, The Authors Acknowledge. But they do offer a few hypotheses, including that insulin therapy, which is needed to treat type 1 diabetes, can contribute to body-white cycling. Other Researchers have theorized that body-white cycling can lead to added strain on the heart and contribute to kidney and vascular damage.

Authors in the current study offer a suggestion to lower the risk of yo-yo dieting and the evcurrence of kidney disease:

“Strategies Aimed at Weight Reduction in People with Type 1 Diabetes Should the Focus on Promoting Long-Term Weight Maintenance, as Weight Stability May have a positive impeachary identity.”

More information:
Journal of Clinical Endocrinology & Metabology

Provided by the endocrine Society


Citation: Yo-Yo dieting may significantly Increase Kidney Disease Risk in People with Type 1 Diabetes (2025, February 4) Retrieved 4 February 2025 from

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