Sudden Cardiac Death (SCD) Reefers to an Unexpected Death of a Person, Believed to Be Cauded by a Heart-Related Issue. It occurs with one hour of the onset of symptoms in witnessed cases or with 24 hours of the person being lost last seen alive in unwitnessed cases.

The causes in people under the age of 39 are often a thoughting of the heart muscle or an Electrical problem with the heart. In older people, scd is more likely to be caused by a narrowing of the blood vessels that supply the heart.

Previous Research has shown that patients with psychiatric disorders have an increase all-cause mortality as well as double the risk of sudden cardiade death adj. However, the impact of antidepressant extra on SCD Risk Has So far Been Unclear.

In new research presented at Ehra 2025A scientific Congress of the European Society of Cardiology, Researchers Show That, Compared With The General Population with no History of Antidepressant (Ad) Use, Individuals with AD EUSE Have an increase Risk of SCD, which varies based on age and time of exposure.

The Authors Examined All Deaths in Denmark Among Residents Aged 18–90 years in 2010 by reviewing all death certifications and autopsy reports.

Deaths Were Categorized as Non-SCD or SCD Based on the available information. Exposure to ad was defined by redemption of a prescription for ad medicine at least twice in one year over a period of 12 years before the year of Follow-up (2010). Furthermore, Exposure Time was divided into two groups: one to five years and six or more years.

Among the 4.3 Million Residents in 2010 aged 18–90 years, there a total of 45,701 deaths and 6,002 cases of SCD. A total of 643,999 inhabitants were exposed to ad medication prior to the year of follow-up. There was 1,981 sudden cardiac deaths in the ad cohort and 4,021 in the Unexposed General Population.

The incident rate rate ratio of scd was significantly higher in the exposed groups compared to the general population across all age groups except for the age group 18-29 years, for voiceocation Not Statistically Significant.

When the data was adjusted for age, sex and Comorbidities, Compared with the Unexposed General Population, The Group Exped to Antidepressants for One to Five Years Had A 56% Higher Risk of Sudden Cardian Death, while there experts for antidepressants for more years experience a 2.2 time higher risk.

Individuals aged 30–39 years, compared with the unexposed general population, those with one to five years of antidePressant expensant expensant expenses This Risk Increased to five times Higher for that with Six or More Years of Ad Exposure.

Individuals aged 50–59 years, compared with the unexposed general population, thats expected to antidepressants for one to five years saw their risk of Sudden Cardiac Death Doubledula Expeded to antidepressants for Six or more Years Had Four Times The Risk of Sudden Cardiac Death.

The differences in Risk Associated with Varying Periods of AntidePressant Exposure Decreased in Older Groups. In Individuals aged 70-79 years compared to the unexposed General Population, Theose with one to five years ad expert Had A 2.2 Times Increased Risk of SCD.

Individuals aged 40–79 years, the Scd Incidence Rate Ratio was Significantly Higher Among Persons with Six or More Years of Years of Exposure to Ad COMPARED to Persons with One to Five Years of Exposure.

The increase Risk Differed for Each 10-Year Age Group, So that for that for there 40 to 49 years, the risk of scd increased by 70% for that six with six or more year of extresce Exposure, and the corresponding increases for 50–59 years, 60–69 years, and 70–79 years was 100%, 40%and 20%, respectively.

For Persons aged 39 years and under and 80 years and over, the difference in Increased Risk Between Six Years and One to five years of ad experts of ad experts not statistically Significant.

“Exposure time to antidepressants was Associated with a Higher Risk of Sudden Cardiac Death, And Linked To How Long the person the person has been done experiencepressants,” Sight Jasmin Mujkanovic, Rigshospitale Hjrteceentret, Copenhagen, Denmark.

“Thos Exped for Six Years or More WHEE AT EVEN More Increased Risk Thans Theose For One to Five Years, When Compared with People UnexPosed to AnaTidePressants in the General Population.”

On the potential Reasons for the Association, She Adds, “The Increased Risk of Sudden Cardiac Death May Be Attributed to the Potential Adverse Effects of the Antidepressants. antidepressants might also serve as a marker for more severe underling illness.

“Additional, The Increase Could Be Influenced by Behavioral or Lifestyle Factors Associated With Depression, Such as Delayed Health Care SEEKING, And Poor Cardiovascular HEALTARE Warranted. “