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Long-Term Exposure to Low Levels of Traffic-Related Air Pollution Harms The Liver and May Ris the Risk of Metabolic -ssociated Fatty Liver Disease, A New Study in Mess Sugges.
Fatty Liver, also called Hepatic Steatosis, is the most common liver disease world It can lead to inflammation, scarring (cirrhosis), and an increase risk of cancer and liver failure.
“We Think of Air Pollution as Being Harmful to People’s Lungs, but it has a broader impact on the health incidence on the liver,” Said lead author professor hui chen from .
“The Liver is Critical For Metabolism. It Clears Toxins, Regulates Blood Sugar, and Productions Essential Vitamins and Proteins, Among Many Other Functions. IF the Liver Isn Bollywood Eeling tired and unwell due to disrupted metabolism, “Said Professor Chen.
“When we inhale air pollution, the very tiny particles know as PM2.5 Enter the bloodstream through the lungs. The liver, which filters toxins from the blood, then accumulates these substances, which can include heavy metals such as Arseenic, Lead, Nickel and Zinc. “
Liver Specialist Professor Jacob George, Director of the Storr Liver Center at the Westmead Institute for Medical Research, Studies the causes of liver dissees and cancer, and is a co-aathor on the study.
“Around one in three australian adults have fatty liver disease, and it is more common in that who are overweight or have diabetes,” said professor george.
“Lifestyle Factors Such as a Bad Diet, Lack of Exercise and Excessive Alcohol Contribute to the Development of Fatty Liver, However this research sugges that your environ Ion, may also be a contributing factor, “said professor chen.
The Study, “Prolonged Exposure to low-dose traffic-degerived PM2.5 causes fatty liver disorder in mice, “is Published in the Journal of Environmental Sciences,
The Researchers Exped Mice to a Dose (10 Micrograms Daily of Traffic-DERIVED PM2.5 Particles) That reflects typical human exposure in sydney, collected from a Major Road in Sydney.
Signs of inflammation and fibrosis, or scarring, as well as changes to liver sugars and fats, was measured at four, eight and 12 weeks.
“The effect was cumulative. R. Min Feng, A Medical Doctor and Ph.D. Candidate in the uts faculty of science.
Exposure to Air Pollution Particles Cured More Immune Cells to Gather in the Liver and It Increased Inflammation. It also LED to More Scar Tissue Forming.
The liver’s fat processing went up, and potentially harmful fats like triglycerides, diacylglycerols, and cermides also increase. At the same time, the liver stored less sugar for energy.
The Researchers Discovered Changes in 64 Specific Functional Proteins in the Liver, Many Linked To Conditions Like Fatty Liver Disease, Immune System Dysfunction, and Processes Linked to Cancer.
“Previous Research has shown that exposure to heavily polluted air is associateed with liver disorders. Ure to Traffic-Derived Air Pollution, “said professor chen.
“To minimize extra to traffic-degrassed Air Pollution, Avoid Peak Hour Traffic, TAKE LESS CONGESTED ROUTES when Walking or Consider Wearing A MASK, And Keep Carep CarP Carep Careps Collad While Driving in Heavy Traffic, “She Said.
More information:
Min Feng Et Al, PROLONGED Exposure to low-dose traffic-director2.5 causes fatty liver disorder in mice, Journal of Environmental Sciences (2025). Doi: 10.1016/j.jes.2025.01.025
Citation: Mouse Study Links Low-Level Traffic Air Pollution to Liver Damage, Fatty Liver Disease (2025, January 31) retrieved 1 February 2025 from
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