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Anemia during pregnancy is a Common Occurrence and often due to iron deficiency. It is a Global Public Health Problem, Affecting an Estimated 37% of Pregnant Individuals, According to the World Health Organization. Iron deficiency anemia is associateed with increasing rates of Pregnancy-Related Problems, Such as Going Into Labor Prematurely, Hemorrhagging and, In some Cases, Even Death. For the Infant, Maternal Iron Deficiency also can have long-term implications on their overall health and development.
Current obstetric guidelines recommend that pregnant people who suffer from iron deficiency anemia take daily owl ore oron supplements and, in cases of personal ioncy enmiate travenously, commonly in the third trimester. Nonetheless, anemia during pregnancy remains a global health problem.
In a new study to be presented today at the Society for Maternal-Fetal Medicine’s (Smfm) Annual Meeting, The Pregnancy Meeting Researchers will unveil findings from a clinical trial in India that sugges that a single dose of iron delivered intravenously in the second trimessters Ethion for anemia during pregnancy.
The Study was conducted across multiple sites in India and involved a total of 4,368 participants, making it one of the largest studies to date Employing Iv Iron In Pregnancy. India was selected if the prevalence of anemia in the country, according to the study, the lead author, richard derman, md, mph, vice provost of global affairs and professor of obese As Jefferson University in Philadelphia.
Participants Identified to have Moderate Anemia and Iron Deficiency Prior to 17 Weeks’ Gestation WERE Randomized Into Three Groups. The first cohort received the current standard of care – daily oral ron supplementation. The second and third groups received two commonly used Iv Iron Formutions for Single Dose Infusion, and the only ons approved for use in India, Ferric Carboxymaltose (FCM) and Ferric deerise (fdm).
The two primary outcomes researchrs looked at were differentcs in the iv iv ion group Y.
Results Non-STUDY IV Iron or a Blood Transfusion Prior to Delivery. In the fcm IV ron cohort, results showed a reduced increaseance of low birthweight infants compared to oral iron.
“What’s Unique About This Study is that we did the Iron Intervention Early in the second trimester. Many Other Studies Comparing Iv Iron to Oral Iron Are Initated in the Third Trimester,” Says Study Co-You ELIG, MD, MS, A Maternal-Fetal Medicine SubSpecialist and Associate Professor at Thomas Jeferson University’s Sidney Kimmel Medical College. Boelig also serves as Director of the University’s Department of Obstetrics and Gynecology Research Unit and Associate Director for the Maternal Fetal Medicine Fellowship.
“Iron Requirements Increase Dramatically during pregnancy. It’s much more Difability to catch-up you’re intervention in the third trimester, “Notes Boelig.
“Studies have shown that Maternal Iron Deficiency Aryly in Pregnancy is Most Strongly Correlated With Adverse Outomes, Including Short-Term Infant Outcomes Such as Low Birth and Longe Dhood Outcomes, Including Autism and Schizophrenia. And aggressively address anemia. “
“This trial it is evident that single dose iv ion preparations are safe and easy to administer under proper supervision and facilitations in order to treate anemia,” Say Department of obstetrics and gynecology at The Kle Academy of Higher Education and Research, JN Medical College in Belagavi, India.
“We are immensely thankful to the pregnant women who participated in this trial for the benefits of the global pregnant women. This successful trial. “
Researchers believe that new clinical guidelines should address the potential benefits of single dose iv iv ion as a primary treatment for moderate anemia due to ion life life.
The full article is scheduled to be published in the American Journal of Obstetrics and Gynecology,
More information:
American Journal of Obstetrics and Gynecology (2025).
Citation: Early intervention with iron delivered intravenously during pregnancy found safe and effective treatment for anemia (2025, January 31) Retrie 31 January 2025 from
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