Health

Early adult binge drinking has lasting impact on aging brain in mice

Early adult binge drinking has lasting impact on aging brain in mice

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New research shows lasting effects of alcohol after a period of abstinence. GABAergic neurons (left) increase in excitatory drive, while pyramidal neurons (right) decrease their ability to talk to other neurons. Credit: Crowley Laboratory / Penn State. Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to …

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Experts define elements of brain-based visual impairment in children

Experts define elements of brain-based visual impairment in children

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Credit: CC0 Public Domain Experts convened by the National Institutes of Health (NIH) have identified five elements of a brain-based condition that has emerged as a leading cause of vision impairment starting in childhood in the United States and other industrialized nations. Known as cerebral (or cortical) visual impairment (CVI), some estimates suggest that at …

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How colliding genetic processes drive aggressive cancers

How colliding genetic processes drive aggressive cancers

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Loss of CDK12 promotes large TD formation. Credit: Nature Cancer (2024). DOI: 10.1038/s43018-024-00848-4 Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem …

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Using in-ear microphones to spot early signs of Alzheimer’s disease

Using in-ear microphones to spot early signs of Alzheimer’s disease

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The researchers will track abnormal saccades, an early sign of Alzheimer’s, using both eye-tracking technology and in-ear hearables. Credit: Boutros et al. Alzheimer’s disease affects more than 50 million people worldwide, often devastating both the individuals who have it and their families and loved ones. It has no known cure, and the slow, progressive nature …

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Why it’s important to take a week off from the gym every now and again: The science behind ‘deload weeks’

Why it’s important to take a week off from the gym every now and again: The science behind ‘deload weeks’

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Credit: Pixabay/CC0 Public Domain If you were to think about the key to getting fit, you’d probably imagine you need to spend plenty of time in the gym. But many fitness influencers claim that taking time away from the gym every six to eight weeks—known as a “deload week”—is actually the key to improving fitness …

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District hospitals are key to unlocking Global South surgical conundrum, says study

District hospitals are key to unlocking Global South surgical conundrum, says study

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Credit: Pixabay/CC0 Public Domain Patients attending first referral hospitals in low- and middle-income countries (LMICs) receive surgical care that is just as safe and effective as that provided by higher level referral centers, reveals a new study in BMJ Global Health, Researchers found no significant difference in 30-day mortality rates between first referral (district) hospitals …

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AI advice influences radiologist and physician diagnostic decisions incorrectly, according to new study

AI advice influences radiologist and physician diagnostic decisions incorrectly, according to new study

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Chest radiograph (CXR) examples of (A, C) local (feature-based) AI explanations and (B, D) global (prototype-based) AI explanations from a simulated AI tool, ChestAId, presented to physicians in the study. In all examples, the correct diagnostic impression for the radiograph case in question is “right upper lobe pneumonia,” and the corresponding AI advice is correct. …

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Controlled experiment investigates how jet lag can disrupt metabolism

Controlled experiment investigates how jet lag can disrupt metabolism

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Credit: iScience (2024). DOI: 10.1016/j.isci.2024.111161 A new study from the University of Surrey and the University of Aberdeen has found that disruptions to our body clock, such as those experienced during jetlag, impact our metabolism—but to a lesser extent than sleepiness and the primary clock in the brain. Led by Professor Jonathan Johnston at the …

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Predicting mood episodes using wearable devices: A sleep and circadian rhythm data analysis model

Predicting mood episodes using wearable devices: A sleep and circadian rhythm data analysis model

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Study framework for predicting mood episodes from sleep pattern information using machine learning (ML) classification algorithm. Credit: npj Digital Medicine (2024). DOI: 10.1038/s41746-024-01333-z The research team led by Chief Investigator Kim Jae Kyoung (IBS Biomedical Mathematics Group, and Professor at KAIST) and Professor Lee Heon-Jeong (Korea University College of Medicine) has developed a novel model …

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Competitive swimming program for young people with severe cerebral palsy reverses motor decline

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

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ParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of Queensland A competitive swimming program developed by University of Queensland researchers for young people with severe cerebral palsy has reversed motor decline associated with the condition. Professor Sean Tweedy from UQ’s School of Human Movement and Nutrition Sciences and the Queensland …

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