Credit: Pixabay/CC0 Public Domain For the first time since 2021, a pill used to help people quit smoking—varenicline—will again be available from the NHS. Varenicline is one of the most effective ways to quit smoking and is deemed an “essential medicine” by the World Health Organization. What is this ‘new’ smoking cessation pill? Varenicline, is …
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Credit: Pixabay/CC0 Public Domain High cardiorespiratory fitness is associated with better cognitive performance and lower risk of dementia in the long term, including in people with a genetic predisposition to dementia, show the findings of a study published online in the British Journal of Sports Medicine, Cardiorespiratory fitness (CRF) is the capacity of the circulatory …
High cardiorespiratory fitness linked to lower risk of dementia Read More »
A boy is supported by his family and care team as a child but feels left with questions as an adult. Credit: Justine Ross, Michigan Medicine In the United States, there are currently more adults living with cerebral palsy than children. Despite this, the Centers for Disease Control and Prevention still label cerebral palsy as …
Cyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebert, Inc. Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene TherapyTo improve the efficacy of gene therapy when using …
A new strategy to enhance gene therapy for sickle cell disease Read More »
Pain intensity scores during the study period. The median is represented by the bold horizontal line within the box. The box defines the IQR. LDK, low-dose ketamine; NRS, Numeric Rating Scale. Credit: Academic Emergency Medicine (2024). DOI: 10.1111/acem.14983 A study that investigates low-dose ketamine (LDK) as an adjunct to morphine for treating acute pain has …
Low-dose ketamine shows promise for pain relief in emergency department patients. Read More »
New research shows lasting effects of alcohol after a period of abstinence. GABAergic neurons (left) increase in excitatory drive, while pyramidal neurons (right) decrease their ability to talk to other neurons. Credit: Crowley Laboratory / Penn State. Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to …
Early adult binge drinking has lasting impact on aging brain in mice Read More »
Credit: CC0 Public Domain Experts convened by the National Institutes of Health (NIH) have identified five elements of a brain-based condition that has emerged as a leading cause of vision impairment starting in childhood in the United States and other industrialized nations. Known as cerebral (or cortical) visual impairment (CVI), some estimates suggest that at …
Experts define elements of brain-based visual impairment in children Read More »
Loss of CDK12 promotes large TD formation. Credit: Nature Cancer (2024). DOI: 10.1038/s43018-024-00848-4 Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem …
How colliding genetic processes drive aggressive cancers Read More »
The researchers will track abnormal saccades, an early sign of Alzheimer’s, using both eye-tracking technology and in-ear hearables. Credit: Boutros et al. Alzheimer’s disease affects more than 50 million people worldwide, often devastating both the individuals who have it and their families and loved ones. It has no known cure, and the slow, progressive nature …
Using in-ear microphones to spot early signs of Alzheimer’s disease Read More »
Credit: Pixabay/CC0 Public Domain If you were to think about the key to getting fit, you’d probably imagine you need to spend plenty of time in the gym. But many fitness influencers claim that taking time away from the gym every six to eight weeks—known as a “deload week”—is actually the key to improving fitness …