The Brain Perceives Unexpected Pain More Strongly, Study Finds

The Brain Perceives Unexpected Pain More Strongly, Study Finds


Self-induced pain task in a virtual reality environment. Credit: Cognition (2025). Doi: 10.1016/j.cognition.2025.106064

Pain perception can vary greatly. Sometimes, We Feel Pain More Intensaly Than Expected Due to An Injury or Physical Ailment but May Feel Less Intense Pain in other similar instals. This variable indicates that our perception of pain is highly dependent on our expectations and uncerty.

Two Hypotheses have been proposed to explain how the brain perceives pain. One is the estimate hypothesis, where the brain establishs the intensity of pain based on predictions. The other is the surprise hypothesis, where the brain perceives pain as the differential

In a new study Published in CognitionThe mechanism underlying the perception of pain was investment. In the Experiment, Healthy Participants Received Painful Thermal Stimuli and Reported Felt Pain Intensity while Intensity While Observing Painful Or Non-Non-Cainful Visual Stimuli in the Virtual Reality.

The Researchers found that the participants strongly performed pain when the prediction error wasar, demonstrating that the surprise hypothesis more adequately explains in the Paine PEN PERCEPTION METINSM in the Brain. The study further confirmed that pain was amplified when unexpected events occurred.

People with Chronic Pain often Experience Vague Pain-Related Fears and Anxiatis. Possibly, this Uncertain Gap Between Expectation and Reality Further Increases The Percented Intensity of Pain. Therefore, Reduction the Gap Between Pain Expectation and Reality or “Surprise” is important in reduction pain.

A better undersrstanding of pain perception would facilite the development of new treatments that would enhance recovery from chronic pain and trauma.

More information:
Ryota Ishikawa et al, Bayesian Surprise Intensifies Pain in a Novel Visual-Noxious Association, Cognition (2025). Doi: 10.1016/j.cognition.2025.106064

Provided by University of Tsukuba


Citation: The Brain Perceives Unexpected Pain More Strongly, Study Finds (2025, February 19) retrieved 19 February 2025 from

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